Tuba Yılmaz

EDUCATION

College / University

Middle East Technical University

Highest Degree

Bachelor of Science

Major Subjects

Molecular Biology and Genetics

Country

Turkey

Lab Experience

CRISPR/Cas9-Mediated Genome Editing, Confocal Microscopy, Image Analysis (Fiji: ImageJ), Flow Cytometry, Molecular Cloning (Designing primers and sgRNAs, gradient PCR, PCR, Restriction Digestion, Ligation, Transformation and Transfection), qRT-PCR, Data analysis by MS Office Excel and R language, Plant (Arabidopsis thaliana) growth experiments and genotyping by PCR and agarose gel electrophoresis, microbiology techniques, SDS-PAGE and Western Blotting

Projects / Research

01/2024-06/2024: Undergraduate Researcher at Neurobiology of Disease Lab (Assoc, Prof, Erkan Kiriş), Middle East Technical University, Ankara, Turkey – “PiT-2 plasmid construction” observation of iPSC research in Fahr’s disease
07/2023-09/2023: Summer Research Internship at Plant Cell Wall Signaling Lab (Prof. Sebastian Wolf), University of Tübingen Center of Plant Molecular Biology, ZMBP, Tübingen, Germany – “Nitrate signaling in RLP44 mediated cell wall homeostasis”, “KO effects of RLP44 and LGO in cell wall signaling”, “Effect of Nitrate on polyploidy in Arabidopsis thaliana”
08/2022-09/2022: Summer Internship at Biochemistry, Microbiology, and Hematology Lab, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey – HCV, HBV, CMV diagnosis testing, patient blood sample biochemical and hormonal analysis, leukemia patient blood analysis via flow cytometry

Scholarships / Awards

2024 – 2025:	Stipend by the International Max Planck Research School
2020 – 2024:	TÜBİTAK BIDEB 2205-Undergraduate Scholarship Program
2023:	Erasmus+ EU Traineeship Grant

SCIENTIFIC INTERESTS AND GOALS

As a graduate student with a molecular biology background and a neurology focus, I’m highly fascinated by the molecular mechanism of the regulatory pathways within cells. I have always found molecular signaling mechanisms interesting and have been involved in gene knockout studies to observe the physiological effects in different subjects. Moreover, I am deeply interested in the pathological pathways of neurodegenerative diseases, such as Alzheimer’s Disease and Multiple Sclerosis. My passion for research involves the study of protein aggregation, neuronal cell death, neurotransmitter signaling, and myelination, which are the significant factors in these diseases. Furthermore, I aim to improve my studies in high-resolution microscopy techniques to observe protein interactions and electrophysiological techniques to observe the electrochemical gradients. I also found the iPSC and stem cell research an exciting area to study and understand the pathology of neurodegenerative diseases. Therefore, I would like to research the molecular pathology of neurodegenerative diseases while improving my scientific skills to understand and find treatments for these complex conditions.